Which peptides are legal in 2026, and which can you get prescribed?
The short answer
Since October 28, 2026, HHS lets licensed 503A pharmacies compound six peptides for patients with a prescription: BPC-157, TB-500, MOTS-c, Epitalon, Semax and KPV, single-ingredient and in set forms. None is FDA-approved. Peptides.build prescribes three of them (BPC-157, MOTS-c, Epitalon) from $158/mo. Blends and DSIP are outside the policy; we still offer them when a licensed provider prescribes them, and we say so on every page.
Status and price of every peptide at Peptides.build
| Protocol | Status | Detail | From | |
|---|---|---|---|---|
| BPC-157 | Covered by HHS policy | Acetate; injection, oral or topical. Single ingredient. | $158/mo | Start |
| MOTS-c | Covered by HHS policy | Acetate; injection (SC or IM). Single ingredient. | $158/mo | Start |
| Epitalon | Covered by HHS policy | Acetate; injection, intermittent courses. Single ingredient. | $158/mo | Start |
| Tesamorelin | FDA-approved brand exists | FDA-approved as Egrifta for HIV-associated lipodystrophy. Compounded tesamorelin is not that product and is not FDA-approved. | $158/mo | Intake coming soon |
| Compounded Semaglutide | FDA-approved brand exists | Branded semaglutide is FDA-approved. Compounded semaglutide is not FDA-approved. | $68/mo | Start |
| Compounded Tirzepatide | FDA-approved brand exists | Branded tirzepatide is FDA-approved. Compounded tirzepatide is not FDA-approved. | $118/mo | Start |
| DSIP | Voted against, outside policy | FDA's advisory committee voted against DSIP in July 2026. Prescribed only when a licensed provider decides it is appropriate. | $158/mo | Start |
| Kisspeptin | Not named in the policy | Not one of the six peptides in the policy. | $158/mo | Start |
| GHK-Cu | Not named in the policy | Not one of the six peptides in the policy. | $158/mo | Start |
| Wolverine Stack | Blend: outside policy | BPC-157 + TB-500. The policy covers one active ingredient only. | $183/mo | Start |
| Glow Stack | Blend: outside policy | BPC-157 + GHK-Cu + TB-500. One-ingredient rule. | $183/mo | Start |
| KLOW Stack | Blend: outside policy | BPC-157 + GHK-Cu + KPV + TB-500. One-ingredient rule. | $183/mo | Start |
| CJC-1295 / Ipamorelin | Blend: outside policy | Two peptides, neither named in the policy. | $183/mo | Start |
| Tesamorelin / Ipamorelin | Blend: outside policy | Two peptides in one vial. One-ingredient rule. | $183/mo | Start |
| Semax / Selank | Blend: outside policy | Semax is covered only alone and intranasally; this pair is outside the policy. | $183/mo | Start |
TB-500, Semax and KPV are covered by the policy but not offered here as single-ingredient protocols yet.
The three covered peptides we prescribe: single-ingredient, from a licensed 503A pharmacy, already mixed.
What does each status mean?
- Covered by HHS policy. HHS will not take enforcement action against a licensed 503A pharmacy or physician compounding it for a patient with a prescription, if the ten conditions are met. Not FDA approval.
- FDA-approved brand exists. A branded drug with the same active ingredient is FDA-approved. The compounded version is a different product and is not FDA-approved.
- Blend: outside policy. The policy covers one active ingredient per product. We still offer these blends when a licensed provider prescribes them.
- Not named in the policy. The policy says nothing about it either way.
The full policy, its ten conditions and its timeline are in our HHS peptide policy explainer.
Prescribed by a provider. Made by a pharmacy. Verified.
Prescribed by a licensed US provider, made by a licensed 503A pharmacy, verified on HealthProtect.
FAQ
Are peptides legal in the US?
It depends on the peptide. FDA-approved peptide drugs are legal by prescription. Since October 28, 2026, six unapproved peptides may be compounded by licensed 503A pharmacies for patients with a prescription under an HHS policy. Research-use-only peptides are not sold for human use.
Which six peptides does the HHS policy cover?
BPC-157, TB-500, MOTS-c, Epitalon, Semax and KPV, each in one chemical form and by specific routes only.
Are peptide stacks and blends legal?
Blends are outside the HHS policy, which covers one active ingredient only. Peptides.build still offers its blends when a licensed provider prescribes them, compounded by a licensed 503A pharmacy, and labels them as outside the policy.
Is DSIP covered?
No. FDA's Pharmacy Compounding Advisory Committee voted against DSIP in July 2026, and it is not in the policy.
Do I need a prescription for peptides?
For anything compounded under the HHS policy, yes: a patient-specific prescription from a licensed clinician, filled by a state-licensed pharmacy.
Are compounded peptides FDA-approved?
No. Compounded medications are not FDA-approved.
Can my state ban a peptide the policy covers?
Yes. State pharmacy and medical boards can still restrict peptides. Check your state before you start.
Tired of reconstituting?
A licensed US provider reviews a short online intake. If a prescription is appropriate, a licensed US 503A pharmacy fills it and ships it cold-chain, already reconstituted and labeled with the concentration.
This page is educational and is not medical advice. Compounded medications are not FDA-approved. No results are implied or guaranteed. A licensed provider decides whether any protocol is appropriate for you, and sets any dose.