MOTS-c CalculatorDosing chart in units, reconstitution and mg-scale draws
Turn the MOTS-c dose on your prescription into units on a U-100 insulin syringe, for a powder vial you reconstitute or a pre-mixed vial from a pharmacy.
Draw to
80units
0.8 mL on a 1 mL U-100 syringe
- Concentration
- 5 mg/mL
- Per unit
- 50 mcg
- Dose
- 4,000 mcg
- Doses per vial
- 2
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Start your MOTS-c visit · from $158/moQuick answer: how do you calculate MOTS-c units?
To calculate MOTS-c units, divide the milligrams in the vial by the millilitres of liquid to get the concentration, divide your prescribed dose in milligrams by that concentration to get the volume, then multiply the volume in mL by 100 for units on a U-100 syringe. MOTS-c doses are written in milligrams, not micrograms, so the draws are large. Example: a 10 mg vial with 2 mL of bacteriostatic water is 5 mg/mL, so if your prescription says 4 mg, you draw 0.8 mL, which is 80 units.
MOTS-c dosing chart in units
Units to draw on a U-100 syringe for common MOTS-c vial sizes and water volumes. Find your vial on the left and read across to the dose on your prescription. This is a conversion table, not a dosing recommendation; a dash means the dose is larger than the vial.
| Vial | Water | mg/mL | 1 mg | 2.5 mg | 4 mg | 5 mg | 10 mg |
|---|---|---|---|---|---|---|---|
| 5 mg | 1 mL | 5 | 20 | 50 | 80 | 100 | – |
| 5 mg | 2 mL | 2.5 | 40 | 100 | >100 | >100 | – |
| 10 mg | 1 mL | 10 | 10 | 25 | 40 | 50 | 100 |
| 10 mg | 2 mL | 5 | 20 | 50 | 80 | 100 | >100 |
| 10 mg | 3 mL | 3.33 | 30 | 75 | >100 | >100 | >100 |
| 10 mg | 5 mL | 2 | 50 | >100 | >100 | >100 | >100 |
| 40 mg | 2 mL | 20 | 5 | 12.5 | 20 | 25 | 50 |
| 40 mg | 4 mL | 10 | 10 | 25 | 40 | 50 | 100 |
Values in units (U-100). 1 unit = 0.01 mL.
Pre-mixed MOTS-c: reading the pharmacy label
MOTS-c calculators online assume a 10 mg freeze-dried vial, and they disagree about the water: some use 2 mL (5 mg/mL), some 3 mL (3.33 mg/mL), some 5 mL (2 mg/mL). None of that applies to a compounding pharmacy prescription, which usually arrives as a liquid with the concentration printed on the label in mg/mL.
Divide your prescribed dose in mg by the label concentration to get mL, then multiply by 100 for units. Because MOTS-c doses are in whole milligrams, a 10 mg/mL label keeps the draw small (4 mg is 40 units) while a 5 mg/mL label doubles it (80 units). Check the result against your syringe size before drawing. Switch the calculator above to Pre-mixed vial and type the label strength.
The label also shows the beyond-use date. Doses per vial only count until that date: a 10 mg vial holds two 4 mg doses, with 2 mg left over that cannot be made into a third.
label: 10 mg/mL prescription: 4000 mcg (4 mg)
4 mg ÷ 10 mg/mL = 0.4 mL
0.4 mL × 100 = 40 unitsTired of reconstituting?
MOTS-c prescribed through Peptides.build arrives already reconstituted by a licensed US 503A pharmacy, labeled with the concentration and ready to draw. Your provider tells you how many units.
Start your MOTS-c visit · from $158/moHow much BAC water for 10 mg or 40 mg of MOTS-c
Use the volume your pharmacy or prescriber specifies. The water changes only the concentration, never the amount of MOTS-c in the vial: more water means more units for the same dose.
| Water | mg/mL | mcg per unit |
|---|---|---|
| 1 mL | 10 | 100 |
| 2 mL | 5 | 50 |
| 3 mL | 3.33 | 33.3 |
| 5 mL | 2 | 20 |
| Water | mg/mL | mcg per unit |
|---|---|---|
| 2 mL | 20 | 200 |
| 4 mL | 10 | 100 |
| 5 mL | 8 | 80 |
| 8 mL | 5 | 50 |
When MOTS-c units do not fit the syringe
The common MOTS-c problem is the opposite of most peptides: the draw is too big, not too small. At 5 mg/mL a 4 mg dose is 80 units, which only fits a 1 mL syringe, and a 5 mg dose from a 10 mg vial mixed with 3 mL is 150 units, which fits no insulin syringe at all. The calculator flags any draw larger than the syringe you selected.
If the result exceeds 100 units, ask your pharmacist or prescriber whether a higher concentration (less water for the same vial) fits your dose. Do not change the amount of water on your own, and do not split a dose into two injections unless the prescriber says so.
New to syringe units? The general peptide calculator has a units-to-mL table and a side-by-side of 0.3, 0.5 and 1 mL syringes.
MOTS-c calculator FAQ
How many units of MOTS-c do I draw?
Units = dose (mg) ÷ concentration (mg/mL) × 100. For a 10 mg vial mixed with 2 mL (5 mg/mL), a prescription of 4 mg is 0.8 mL, or 80 units on a U-100 syringe. The dose itself comes from your prescription.
How much bacteriostatic water do I add to 10 mg of MOTS-c?
Use the volume your pharmacy or prescriber specifies. The water does not change the amount of MOTS-c, only the concentration: 1 mL makes 10 mg/mL (100 mcg per unit), 2 mL makes 5 mg/mL (50 mcg per unit) and 5 mL makes 2 mg/mL (20 mcg per unit). Peptides.build prescriptions arrive pre-mixed, so patients never add water.
How much bacteriostatic water do I add to 40 mg of MOTS-c?
Follow the pharmacy's instructions. With 40 mg: 2 mL makes 20 mg/mL (200 mcg per unit), 4 mL makes 10 mg/mL (100 mcg per unit) and 8 mL makes 5 mg/mL (50 mcg per unit). Check that the vial can physically hold the volume: many 40 mg vials are 3 mL glass, so 8 mL does not fit.
My MOTS-c vial came pre-mixed. How do I convert my dose to units?
Read the concentration on the pharmacy label, for example 10 mg/mL. Divide your prescribed dose in mg by it to get mL, then multiply by 100: 4 mg ÷ 10 mg/mL = 0.4 mL = 40 units. Choose Pre-mixed vial in the calculator to do this automatically.
Is my MOTS-c dose in mg or mcg?
Check the prescription. MOTS-c is almost always written in milligrams, where most other peptides are written in micrograms. Entering 4 mg as 4 mcg gives a draw 1,000 times too small, and entering 400 mcg for 4 mg gives a draw ten times too small. Set the unit toggle in the calculator to match the prescription exactly.
Why does my MOTS-c vial run out so fast?
Because the doses are large relative to the vial. A 10 mg vial holds two 4 mg doses or four 2.5 mg doses, and the remainder cannot be made into a full dose. The calculator shows doses per vial for the figures you enter so you can plan refills with your pharmacy.
How should MOTS-c be stored once mixed?
Follow the storage line on the pharmacy label. Reconstituted peptides are typically kept refrigerated, not frozen, and used before the beyond-use date. Do not use a vial that looks cloudy or has particles; contact the pharmacy.
Is MOTS-c FDA-approved?
No. MOTS-c is not FDA-approved for any use, and compounded medications are not FDA-approved. When it is prescribed, a licensed provider decides whether it is appropriate for the individual patient.
Is MOTS-c allowed in competitive sport?
No. The World Anti-Doping Agency added MOTS-c to the Prohibited List as an example of an AMP-activated protein kinase (AMPK) activator under S4 (metabolic modulators), prohibited at all times. Drug-tested athletes should check with their governing body.
Does this calculator tell me how much MOTS-c to take?
No. It performs arithmetic only and does not recommend a dose or schedule. The dose, timing and vial strength come from your prescription and pharmacy label.
Get MOTS-c already reconstituted
A licensed US provider reviews a short online intake and sets your dose. A US 503A pharmacy prepares it, labels the concentration and ships it cold-chain, ready to draw.
This calculator performs arithmetic only. It does not recommend doses and is not medical advice. MOTS-c is not FDA-approved, and compounded medications are not FDA-approved. Always follow the dose, concentration and schedule on your prescription and pharmacy label, and confirm any calculation with your pharmacist or prescriber before injecting.