> ## Site index > Full index of Peptides.build at https://peptides.build/llms.txt. Use it to discover every page. # MOTS-c Peptide Prescribed Online, from $158/mo MOTS-c is a peptide encoded in mitochondrial DNA, the part of the cell that produces energy. Prescribed online by a licensed US provider. From $158/mo. URL: https://peptides.build/protocols/mots-c/ 1. [Home](https://peptides.build/) 2. [Protocols](https://peptides.build/protocols/) 3. [Cognitive](https://peptides.build/protocols/cognitive/) 4. MOTS-c ![MOTS-c prescription vial, cognitive protocol from Peptides.build](/media/products/mots-c.webp) Cognitive # MOTS-c PeptidePrescribed online, from $158/mo From **$158**/mo CognitiveInjection MOTS-c is a peptide encoded by mitochondrial DNA, studied for its role in cellular energy metabolism and exercise capacity. It is prescribed by a licensed US provider after an online intake and compounded by a licensed US pharmacy as an injectable protocol. MOTS-c is unusual because it comes from mitochondrial DNA rather than the nucleus. Research interest centers on metabolism and how the body handles training load. It is prescribed only when a provider judges it appropriate. [MOTS-c calculator: units, dosing chart →](https://peptides.build/tools/mots-c-calculator/) ## How much does MOTS-c cost? - Monthly$199billed monthly - 3 months$499≈ $166/mo - 6 months$949≈ $158/moBest value MOTS-c through Peptides.build costs $199 billed monthly, $499 every 3 months, or $949 every 6 months (about $158/mo). The price includes the provider review, compounding by a licensed US 503A pharmacy and cold-chain shipping; there is no separate membership fee. [Start Building](https://start.peptides.build/start-online-visit/mots-c) Pay over time at checkout![Klarna](/media/payments/klarna.png)![Afterpay](/media/payments/afterpay.png)![Affirm](/media/payments/affirm.png) - All protocols are - Made in USA - Physician Guided - Reviewed by Licensed US provider - Fulfilled by 503A US pharmacy - Shipping: Cold-chain, all 50 states ## MOTS-c at a glance Also known as MOTS-c peptide, mitochondrial ORF of the 12S rRNA type-c Compound MOTS-c Form Subcutaneous injection, supplied already reconstituted and labeled with the concentration Goal [Cognitive](https://peptides.build/protocols/cognitive/). Mitochondrial peptide for training capacity. Prescription Required. Online intake reviewed by a licensed US provider; prescribed only when appropriate. Pharmacy Compounded by a licensed US 503A pharmacy, shipped cold-chain to all 50 states ([pharmacy and providers](https://peptides.build/pharmacy-providers/)). FDA status Not FDA-approved; compounded medications are not FDA-approved. Price From $158/mo on the 6-month plan ($199 billed monthly). Free tool [MOTS-c calculator](https://peptides.build/tools/mots-c-calculator/) (units, reconstitution and dosing chart) ## Is MOTS-c legal? Status under the HHS peptide policy **Covered by the HHS policy.** MOTS-c acetate by injection is one of the six peptides HHS now lets licensed 503A pharmacies compound for patients with a prescription. This protocol is single-ingredient. [Legal status explained](https://peptides.build/legal/mots-c/) · [MOTS-c price per month](https://peptides.build/pricing/mots-c/) · [Buy MOTS-c, prescribed](https://peptides.build/buy/mots-c/) · [Every protocol's status and price](https://peptides.build/legal/peptides/) · [All prices](https://peptides.build/pricing/) ## How it works MOTS-c is a peptide encoded in mitochondrial DNA, the part of the cell that produces energy. Research describes MOTS-c as a signaling peptide involved in cellular energy metabolism. Studies have looked at its relationship to how tissue responds to exercise. This is mechanism research, not a promise about performance. ## Who is this considered for? Mitochondrial peptide for training capacity. - Athletes and former athletes focused on metabolic support. - People building a performance protocol around energy metabolism. - Anyone pairing training work with provider-guided care. ## Who should avoid it? - Anyone pregnant, trying to conceive, or breastfeeding. - People with an active cancer diagnosis, unless cleared by their oncologist. - Anyone a provider determines is not an appropriate candidate. Eligibility is always determined by a licensed provider during intake. ## What the research says - 2015 · Animal and cell study ### The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance Cell Metabolism[View citation](https://doi.org/10.1016/j.cmet.2015.02.009) - 2021 · Animal study with human exercise samples ### MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis Nature Communications[View citation](https://doi.org/10.1038/s41467-020-20790-0) Citations retrieved from PubMed. MOTS-c is a compounded medication and is not FDA-approved. The research above is provided for education and does not describe outcomes you should expect. ## Questions No. MOTS-c is a compounded medication prepared by a licensed 503A pharmacy for a specific patient after a prescription. Compounded medications are not reviewed or approved by the FDA the way mass-manufactured drugs are. Yes. You complete an online intake, a licensed US provider reviews it, and MOTS-c is prescribed only if it is appropriate for you. MOTS-c is prescribed as a subcutaneous injection. Your provider sets your specific protocol; we do not publish dosing on this page. Every order is compounded by a licensed US pharmacy and shipped cold-chain to all 50 states. Some of our protocols combine compounds. Whether a combination is appropriate for you is a decision your provider makes during intake. MOTS-c through Peptides.build costs $199 billed monthly, $499 every 3 months, or $949 every 6 months (about $158/mo). The price includes the provider review, compounding by a licensed US 503A pharmacy and cold-chain shipping; there is no separate membership fee. Complete the online intake for MOTS-c (about five minutes), a licensed US provider reviews your history and prescribes it only if it is appropriate for you, a licensed 503A pharmacy compounds it, and it ships cold-chain to your door already reconstituted and labeled with the concentration. You are not charged if the provider decides it is not appropriate. ## How to get MOTS-c prescribed online Complete the online intake for MOTS-c (about five minutes), a licensed US provider reviews your history and prescribes it only if it is appropriate for you, a licensed 503A pharmacy compounds it, and it ships cold-chain to your door already reconstituted and labeled with the concentration. You are not charged if the provider decides it is not appropriate. The full process, timing and what is included are on [how it works](https://peptides.build/how-it-works/). ## Learn more about MOTS-c - [What is MOTS-c?](https://peptides.build/learn/what-is-mots-c/) - [All cognitive protocols compared](https://peptides.build/protocols/cognitive/) ## Often considered alongside MOTS-c Whether any combination fits you is a provider decision made during intake. Related protocols in the catalog: - [Epitalon](https://peptides.build/protocols/epitalon/) - [Kisspeptin](https://peptides.build/protocols/kisspeptin/) - [Tesamorelin](https://peptides.build/protocols/tesamorelin/) MOTS-c is a compounded medication prepared by a licensed US pharmacy after a prescription from a licensed provider. Compounded medications are not FDA-approved. Nothing here is medical advice.